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Eyevensys’ EyeCET technology uses electroporation to deliver protein coding plasmids, which are safe and non-viral, into the ciliary muscle of the eye. This approach facilitates the sustained production of therapeutic proteins, localized within the ciliary muscle cells.
Eyevensys believes its EyeCET technology can improve both short and long-term therapeutic outcomes by greatly enhancing patient compliance and significantly improving the tolerability of treatment.
Eyevensys’ lead product EYS606, a non-viral plasmid encoding anti-TNFα, is a potential new treatment for patients with non-infectious Uveitis (NIU). EYS606 consists of Eyevensys’ proprietary electro-transfection injection system (ETIS) in combination with a plasmid encoding for the production of anti-TNFα, a cytokine that has been shown to play a pivotal role in mediating intraocular inflammation in NIU. EYS606 has been granted an Orphan drug designation by the EMA for the treatment of NIU.
Eyevensys was founded in 2008. It is headquartered in Paris, France, and is funded by Boehringer Ingelheim Venture Fund, BPIFrance, CapDecisif, Inserm Transfert, and Pontifax.